Placement of focal points and leading the eye through the canvas are important in creating successful artwork. I usually feature one main subject and follow the rule of thirds that many landscape artist use; however, I am working to divide my canvas into thirds vertically. I like to place my focal point on the 1/3 line leaving two-thirds of the canvas on the other side. I also tend to put my quote in one of the four hotspots. Where the imaginary 1/3 lines intersect.
A balance of weight is achieved insuring a more interesting layout. I also try to be aware of how colors or patterns create visual weight.
Finally, I tend to make sure I use an odd number of ephemeral pieces. Three and five are typically my tendency.
There are many sources that discuss these principles in greater detail and probably with more accuracy. Take a moment a study some of your favorite artist's works or pieces that you have created. Even magazine ads are a great source for design lessons.